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Characterization of human skin equivalents developed at body's core and surface temperatures

Human skin equivalents (HSEs) are in vitro developed three‐dimensional models resembling native human skin (NHS) to a high extent. However, the epidermal lipid biosynthesis, barrier lipid composition, and organization are altered, leading to an elevated diffusion rate of therapeutic molecules. The a...

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Опубликовано в: :J Tissue Eng Regen Med
Главные авторы: Mieremet, Arnout, van Dijk, Rianne, Boiten, Walter, Gooris, Gert, Bouwstra, Joke A., El Ghalbzouri, Abdoelwaheb
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6767576/
https://ncbi.nlm.nih.gov/pubmed/30945465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/term.2858
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