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Contribution of Palmitic Acid to Epidermal Morphogenesis and Lipid Barrier Formation in Human Skin Equivalents

The outermost barrier layer of the skin is the stratum corneum (SC), which consists of corneocytes embedded in a lipid matrix. Biosynthesis of barrier lipids occurs de novo in the epidermis or is performed with externally derived lipids. Hence, in vitro developed human skin equivalents (HSEs) are de...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Mieremet, Arnout, Helder, Richard, Nadaban, Andreea, Gooris, Gert, Boiten, Walter, El Ghalbzouri, Abdoelwaheb, Bouwstra, Joke A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6928966/
https://ncbi.nlm.nih.gov/pubmed/31810180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20236069
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