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Implementing MR‐PRESSO and GCTA‐GSMR for pleiotropy assessment in Mendelian randomization studies from a practitioner's perspective

With the advent of very large scale genome‐wide association studies (GWASs), the promise of Mendelian randomization (MR) has begun to be fulfilled. However, whilst GWASs have provided essential information on the single nucleotide polymorphisms (SNPs) associated with modifiable risk factors needed f...

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Detalhes bibliográficos
Publicado no:Genet Epidemiol
Main Authors: Ong, Jue‐Sheng, MacGregor, Stuart
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6767464/
https://ncbi.nlm.nih.gov/pubmed/31045282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22207
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