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CLEFMA Activates the Extrinsic and Intrinsic Apoptotic Processes through JNK1/2 and p38 Pathways in Human Osteosarcoma Cells

Due to the poor prognosis of metastatic osteosarcoma, chemotherapy is usually employed in the adjuvant situation to improve the prognosis and the chances of long-term survival. 4-[3,5-Bis(2-chlorobenzylidene)-4-oxo-piperidine-1-yl]-4-oxo-2-butenoic acid (CLEFMA) is a synthetic analog of curcumin and...

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Bibliografiske detaljer
Udgivet i:Molecules
Main Authors: Yang, Jia-Sin, Lin, Renn-Chia, Hsieh, Yi-Hsien, Wu, Heng-Hsiung, Li, Geng-Chung, Lin, Ya-Chiu, Yang, Shun-Fa, Lu, Ko-Hsiu
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6767181/
https://ncbi.nlm.nih.gov/pubmed/31505816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24183280
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