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盐酸右旋美托咪啶通过提高HIF-1α的表达减轻糖尿病大鼠肾缺血再灌注损伤
OBJECTIVE: To verify whether dexmedetomidine hydrochloride (Dex) alleviates renal ischemia-reperfusion (IR) injury in diabetic rats by increasing the expression of hypoxia inducible factor-1α (HIF-1α). METHODS: A rat model of type 2 diabetes mellitus was established by high-fat diet and streptozotoc...
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| 發表在: | Nan Fang Yi Ke Da Xue Xue Bao |
|---|---|
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
南方医科大学学报编辑部
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6765596/ https://ncbi.nlm.nih.gov/pubmed/31511215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12122/j.issn.1673-4254.2019.08.11 |
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