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右美托咪定可能通过SIRT1信号通路减轻老龄大鼠的术后认知功能障碍
OBJECTIVE: To explore the role of silent information regulator 1 (SIRT1) signaling pathway in mediating the effect of dexmedetomidine (DEX) to alleviate postoperative cognitive dysfunction (POCD) in aged rats. METHODS: Seventy-two healthy male Sprague-Dawley rats aged 18-20 months (weighing 500-700...
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| Pubblicato in: | Nan Fang Yi Ke Da Xue Xue Bao |
|---|---|
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
南方医科大学学报编辑部
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6744197/ https://ncbi.nlm.nih.gov/pubmed/30377100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12122/j.issn.1673-4254.2018.09.08 |
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