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MRL-45696减轻2型糖尿病大鼠心肌缺血再灌注后的DNA损伤
OBJECTIVE: To study the protective effect of MRL-45696, an inhibitor of poly(ADP-ribose) polymerase-1 (PARP-1), against DNA damage after myocardial ischemia/reperfusion (I/R) in diabetic rats. METHODS: Rat models of type 2 diabetes mellitus were established by high-fat feeding and a single peritonea...
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| Udgivet i: | Nan Fang Yi Ke Da Xue Xue Bao |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
南方医科大学学报编辑部
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6765544/ https://ncbi.nlm.nih.gov/pubmed/33168502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3969/j.issn.1673-4254.2018.07.10 |
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