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Cell Receptor and Surface Ligand Density Effects on Dynamic States of Adhering Circulating Tumor Cells

Dynamic states of cancer cells moving under shear flow in an antibody-functionalized microchannel are investigated experimentally and theoretically. The cell motion is analyzed with the aid of a simplified physical model featuring a receptor-coated rigid sphere moving above a solid surface with immo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Lab Chip
Hauptverfasser: Zheng, Xiangjun, Cheung, Luthur Siu Lun, Schroeder, Joyce A., Jiang, Linan, Zohar, Yitshak
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6765388/
https://ncbi.nlm.nih.gov/pubmed/21853194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c1lc20455f
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