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PHF2 histone demethylase prevents DNA damage and genome instability by controlling cell cycle progression of neural progenitors
Histone H3 lysine 9 methylation (H3K9me) is essential for cellular homeostasis; however, its contribution to development is not well established. Here, we demonstrate that the H3K9me2 demethylase PHF2 is essential for neural progenitor proliferation in vitro and for early neurogenesis in the chicken...
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| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6765295/ https://ncbi.nlm.nih.gov/pubmed/31488723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1903188116 |
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