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Three archetypical classes of macromolecular regulators of protein liquid–liquid phase separation

Membraneless organelles, corresponding to the droplet phase upon liquid–liquid phase separation (LLPS) of protein or protein–RNA mixtures, mediate myriad cellular functions. Cells use a variety of biochemical signals such as expression level and posttranslational modification to regulate droplet for...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Ghosh, Archishman, Mazarakos, Konstantinos, Zhou, Huan-Xiang
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6765290/
https://ncbi.nlm.nih.gov/pubmed/31506351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1907849116
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