The single-cell transcriptomic landscape of early human diabetic nephropathy

Diabetic nephropathy is characterized by damage to both the glomerulus and tubulointerstitium, but relatively little is known about accompanying cell-specific changes in gene expression. We performed unbiased single-nucleus RNA sequencing (snRNA-seq) on cryopreserved human diabetic kidney samples to...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Wilson, Parker C., Wu, Haojia, Kirita, Yuhei, Uchimura, Kohei, Ledru, Nicolas, Rennke, Helmut G., Welling, Paul A., Waikar, Sushrut S., Humphreys, Benjamin D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2019
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6765272/
https://ncbi.nlm.nih.gov/pubmed/31506348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1908706116
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