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Comparative analysis and refinement of human PSC-derived kidney organoid differentiation with single cell transcriptomics

Kidney organoids derived from human pluripotent stem cells have great utility for investigating organogenesis and disease mechanisms, and potentially as a replacement tissue source, but how closely organoids derived from current protocols replicate adult human kidney is undefined. We compared two di...

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Bibliografische gegevens
Gepubliceerd in:Cell Stem Cell
Hoofdauteurs: Wu, Haojia, Uchimura, Kohei, Donnelly, Erinn, Kirita, Yuhei, Morris, Samantha A., Humphreys, Benjamin D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6324730/
https://ncbi.nlm.nih.gov/pubmed/30449713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2018.10.010
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