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Evolution-based screening enables genome-wide prioritization and discovery of DNA repair genes
DNA repair is critical for genome stability and is maintained through conserved pathways. Traditional genome-wide mammalian screens are both expensive and laborious. However, computational approaches circumvent these limitations and are a powerful tool to identify new DNA repair factors. By analyzin...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6765268/ https://ncbi.nlm.nih.gov/pubmed/31501324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1906559116 |
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