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DNA-PK(cs) promotes chromatin decondensation to facilitate initiation of the DNA damage response

The DNA damage response (DDR) encompasses the cellular response to DNA double-stranded breaks (DSBs), and includes recognition of the DSB, recruitment of numerous factors to the DNA damage site, initiation of signaling cascades, chromatin remodeling, cell-cycle checkpoint activation, and repair of t...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Lu, Huiming, Saha, Janapriya, Beckmann, Pauline J, Hendrickson, Eric A, Davis, Anthony J
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6765147/
https://ncbi.nlm.nih.gov/pubmed/31396623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz694
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