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Circularization of flavivirus genomic RNA inhibits de novo translation initiation

Members of the Flaviviridae family, including dengue virus (DENV) and yellow fever virus, cause serious disease in humans, whilst maternal infection with Zika virus (ZIKV) can induce microcephaly in newborns. Following infection, flaviviral RNA genomes are translated to produce the viral replication...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Sanford, Thomas J, Mears, Harriet V, Fajardo, Teodoro, Locker, Nicolas, Sweeney, Trevor R
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6765113/
https://ncbi.nlm.nih.gov/pubmed/31392996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz686
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