Circularization of flavivirus genomic RNA inhibits de novo translation initiation

Members of the Flaviviridae family, including dengue virus (DENV) and yellow fever virus, cause serious disease in humans, whilst maternal infection with Zika virus (ZIKV) can induce microcephaly in newborns. Following infection, flaviviral RNA genomes are translated to produce the viral replication...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Sanford, Thomas J, Mears, Harriet V, Fajardo, Teodoro, Locker, Nicolas, Sweeney, Trevor R
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
RNA and RNA-protein complexes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6765113/
https://ncbi.nlm.nih.gov/pubmed/31392996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz686
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