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IL-6 Activities in the Tumour Microenvironment. Part 1
The predominant role of IL-6 in cancer is its key promotion of tumour growth. IL-6 binds IL-6 receptor (IL-6R) and the membrane-bound glycoprotein gp130. The complex I-6/IL-6R/gp130 starts the Janus kinases (JAKs) and signal transducer and activator of transcription 3 (STAT3) or JAK/STAT3 pathway. I...
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| Publicado no: | Open Access Maced J Med Sci |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Republic of Macedonia
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6765074/ https://ncbi.nlm.nih.gov/pubmed/31592285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3889/oamjms.2019.589 |
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