Potent Neutralization of Staphylococcal Enterotoxin B in vivo by antibodies that block binding to the T-cell receptor

To develop an antibody (Ab) therapeutic against Staphylococcal Enterotoxin B (SEB), a potential incapacitating bioterrorism agent and a major cause of food poisoning, we developed a “Class T” anti-SEB neutralizing Ab (GC132) targeting an epitope on SEB distinct from that of previously developed “Cla...

詳細記述

保存先:
書誌詳細
出版年:J Mol Biol
主要な著者: Chen, Gang, Karauzum, Hatice, Long, Hua, Carranza, Danielle, Holtsberg, Frederick W., Howell, Katie A., Abaandou, Laura, Zhang, Bojie, Jarvik, Nick, Ye, Wei, Liao, Grant C., Gross, Michael L., Leung, Daisy W., Amarasinghe, Gaya K., Aman, M. Javad, Sidhu, Sachdev S.
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6764902/
https://ncbi.nlm.nih.gov/pubmed/30928493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2019.03.017
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