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Rationally Designed Small Molecules to Prevent Type 1 Diabetes

PURPOSE OF REVIEW: To review the recent findings that small ‘drug-like’ compounds block disease-specific HLA molecules in type 1 diabetes (T1D). RECENT FINDINGS: The predominant genetic risk for developing T1D, the immune mediated form of diabetes, is conferred through human leukocyte antigen (HLA)...

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Detalhes bibliográficos
Publicado no:Curr Opin Endocrinol Diabetes Obes
Main Authors: Ostrov, David A., Gottlieb, Peter A., Michels, Aaron W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6764771/
https://ncbi.nlm.nih.gov/pubmed/30694829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MED.0000000000000470
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