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High-Throughput Quantitative Genetic Interaction Mapping in the Fission Yeast Schizosaccharomyces pombe

Epistasis mapping, in which the phenotype that emerges from combining pairs of mutations is measured quantitatively, is a powerful tool for unbiased study of gene function. When performed at a large scale, this approach has been used to assign function to previously uncharacterized genes, define fun...

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Bibliografiske detaljer
Udgivet i:Cold Spring Harb Protoc
Main Authors: Roguev, Assen, Ryan, Colm J., Hartsuiker, Edgar, Krogan, Nevan J.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6764749/
https://ncbi.nlm.nih.gov/pubmed/28733404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/pdb.top079905
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