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High-Throughput Quantitative Genetic Interaction Mapping in the Fission Yeast Schizosaccharomyces pombe

Epistasis mapping, in which the phenotype that emerges from combining pairs of mutations is measured quantitatively, is a powerful tool for unbiased study of gene function. When performed at a large scale, this approach has been used to assign function to previously uncharacterized genes, define fun...

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Dettagli Bibliografici
Pubblicato in:Cold Spring Harb Protoc
Autori principali: Roguev, Assen, Ryan, Colm J., Hartsuiker, Edgar, Krogan, Nevan J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6764749/
https://ncbi.nlm.nih.gov/pubmed/28733404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/pdb.top079905
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