Hydroxyurea Facilitates Manifestation of Disease Relevant Phenotypes in Patients-Derived IPSCs-Based Modeling of Late-Onset Parkinson’s Disease

Induced pluripotent stem cells (iPSCs)-derived dopaminergic neurons might be reset back to the fetal state due to reprogramming. Thus, it is a compelling challenge to reliably and efficiently induce disease phenotypes of iPSCs-derived dopaminergic neurons to model late-onset Parkinson’s disease (PD)...

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Vydáno v:Aging Dis
Hlavní autoři: Tan, Yuan, Ke, Minjing, Huang, Zhijian, Chong, Cheong-Meng, Cen, Xiaotong, Lu, Jia-Hong, Yao, Xiaoli, Qin, Dajiang, Su, Huanxing
Médium: Artigo
Jazyk:Inglês
Vydáno: JKL International LLC 2019
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Orginal Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6764725/
https://ncbi.nlm.nih.gov/pubmed/31595201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14336/AD.2018.1216
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