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Targeting Cannabinoid 1 and Delta Opioid Receptor Heteromers Alleviates Chemotherapy-Induced Neuropathic Pain

[Image: see text] Cannabinoid 1 (CB(1)R) and delta opioid receptors (DOR) associate to form heteromers that exhibit distinct pharmacological properties. Not much is known about CB(1)R-DOR heteromer location or signaling along the pain circuit in either animal models or patients with chemotherapy-ind...

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Publicat a:ACS Pharmacol Transl Sci
Autors principals: Sierra, Salvador, Gupta, Achla, Gomes, Ivone, Fowkes, Mary, Ram, Akila, Bobeck, Erin N., Devi, Lakshmi A.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2019
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6764458/
https://ncbi.nlm.nih.gov/pubmed/31565698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.9b00008
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