Photobinding of Triflusal to Human Serum Albumin Investigated by Fluorescence, Proteomic Analysis, and Computational Studies

Triflusal is a platelet antiaggregant employed for the treatment and prevention of thromboembolic diseases. After administration, it is biotransformed into its active metabolite, the 2-hydroxy-4-trifluoromethylbenzoic acid (HTB). We present here an investigation on HTB photobinding to human serum al...

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Опубликовано в: :Front Pharmacol
Главные авторы: Molins-Molina, Oscar, Pérez-Ruiz, Raúl, Lence, Emilio, González-Bello, Concepción, Miranda, Miguel A., Jiménez, M. Consuelo
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2019
Предметы:
Pharmacology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6764118/
https://ncbi.nlm.nih.gov/pubmed/31616294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01028
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