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Prioritization of candidate cancer drugs based on a drug functional similarity network constructed by integrating pathway activities and drug activities

Due to the speed, efficiency, relative risk, and lower costs compared to traditional drug discovery, the prioritization of candidate drugs for repurposing against cancers of interest has attracted the attention of experts in recent years. Herein, we present a powerful computational approach, termed...

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Dettagli Bibliografici
Pubblicato in:Mol Oncol
Autori principali: Di, Jieyi, Zheng, Baotong, Kong, Qingfei, Jiang, Ying, Liu, Siyao, Yang, Yang, Han, Xudong, Sheng, Yuqi, Zhang, Yunpeng, Cheng, Liang, Han, Junwei
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763777/
https://ncbi.nlm.nih.gov/pubmed/31408580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12564
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