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Prioritization of candidate cancer drugs based on a drug functional similarity network constructed by integrating pathway activities and drug activities

Due to the speed, efficiency, relative risk, and lower costs compared to traditional drug discovery, the prioritization of candidate drugs for repurposing against cancers of interest has attracted the attention of experts in recent years. Herein, we present a powerful computational approach, termed...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Di, Jieyi, Zheng, Baotong, Kong, Qingfei, Jiang, Ying, Liu, Siyao, Yang, Yang, Han, Xudong, Sheng, Yuqi, Zhang, Yunpeng, Cheng, Liang, Han, Junwei
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763777/
https://ncbi.nlm.nih.gov/pubmed/31408580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12564
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