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Characterization of the Self-Resistance Mechanism to Dityromycin in the Streptomyces Producer Strain

Dityromycin is a peptide antibiotic isolated from the culture broth of the soil microorganism Streptomyces sp. strain AM-2504. Recent structural studies have shown that dityromycin targets the ribosomal protein S12 in the 30S ribosomal subunit, inhibiting translocation. Herein, by using in vitro pro...

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Detalhes bibliográficos
Publicado no:mSphere
Main Authors: Fabbretti, Attilio, Çapuni, Retina, Giuliodori, Anna Maria, Cimarelli, Lucia, Miano, Antonino, Napolioni, Valerio, La Teana, Anna, Spurio, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763770/
https://ncbi.nlm.nih.gov/pubmed/31554724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00554-19
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