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Distinct transcriptional roles for Histone H3-K56 acetylation during the cell cycle in Yeast

Dynamic disruption and reassembly of promoter-proximal nucleosomes is a conserved hallmark of transcriptionally active chromatin. Histone H3-K56 acetylation (H3K56Ac) enhances these turnover events and promotes nucleosome assembly during S phase. Here we sequence nascent transcripts to investigate t...

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Udgivet i:Nat Commun
Main Authors: Topal, Salih, Vasseur, Pauline, Radman-Livaja, Marta, Peterson, Craig L.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763489/
https://ncbi.nlm.nih.gov/pubmed/31558720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12400-5
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