Multiplexed and high-throughput neuronal fluorescence imaging with diffusible probes

Synapses contain hundreds of distinct proteins whose heterogeneous expression levels are determinants of synaptic plasticity and signal transmission relevant to a range of diseases. Here, we use diffusible nucleic acid imaging probes to profile neuronal synapses using multiplexed confocal and super-...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Guo, Syuan-Ming, Veneziano, Remi, Gordonov, Simon, Li, Li, Danielson, Eric, Perez de Arce, Karen, Park, Demian, Kulesa, Anthony B., Wamhoff, Eike-Christian, Blainey, Paul C., Boyden, Edward S., Cottrell, Jeffrey R., Bathe, Mark
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763432/
https://ncbi.nlm.nih.gov/pubmed/31558769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12372-6
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