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Direct wavefront sensing enables functional imaging of infragranular axons and spines
We advance two-photon microscopy for near diffraction-limited imaging down to 850 μm below the pia in awake mice. Our approach combines direct wavefront sensing of descanned fluorescence from Cy5.5-dextran in brain microvessels, which forms a guide star, and adaptive optics to compensate for tissue-...
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| Veröffentlicht in: | Nat Methods |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6763395/ https://ncbi.nlm.nih.gov/pubmed/31209383 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-019-0434-7 |
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