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eIF5B gates the transition from translation initiation to elongation

Translation initiation determines both the quantity and identity of the protein encoded in an mRNA by establishing the reading frame for protein synthesis. In eukaryotic cells, numerous translation initiation factors (eIFs) prepare ribosomes for polypeptide synthesis, yet the underlying dynamics of...

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Dades bibliogràfiques
Publicat a:Nature
Autors principals: Wang, Jinfan, Johnson, Alex G., Lapointe, Christopher P., Choi, Junhong, Prabhakar, Arjun, Chen, Dong-Hua, Petrov, Alexey N., Puglisi, Joseph D.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763361/
https://ncbi.nlm.nih.gov/pubmed/31534220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1561-0
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