Innate and adaptive nasal mucosal immune responses following experimental human pneumococcal colonization

Streptococcus pneumoniae (Spn) is a common cause of respiratory infection, but also frequently colonizes the nasopharynx in the absence of disease. We used mass cytometry to study immune cells from nasal biopsy samples collected following experimental human pneumococcal challenge in order to identif...

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Veröffentlicht in:J Clin Invest
Hauptverfasser: Jochems, Simon P., de Ruiter, Karin, Solórzano, Carla, Voskamp, Astrid, Mitsi, Elena, Nikolaou, Elissavet, Carniel, Beatriz F., Pojar, Sherin, German, Esther L., Reiné, Jesús, Soares-Schanoski, Alessandra, Hill, Helen, Robinson, Rachel, Hyder-Wright, Angela D., Weight, Caroline M., Durrenberger, Pascal F., Heyderman, Robert S., Gordon, Stephen B., Smits, Hermelijn H., Urban, Britta C., Rylance, Jamie, Collins, Andrea M., Wilkie, Mark D., Lazarova, Lepa, Leong, Samuel C., Yazdanbakhsh, Maria, Ferreira, Daniela M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2019
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763269/
https://ncbi.nlm.nih.gov/pubmed/31361601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI128865
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