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Revealing the molecular signaling pathways of mucus stasis in cystic fibrosis

Mucus obstruction is a hallmark of cystic fibrosis (CF) airway disease, leading to chronic infection, dysregulated inflammation, and progressive lung disease. As mucus hyperexpression is a key component in the initiation and perpetuation of airway obstruction, the triggers underlying mucin release m...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Birket, Susan E., Rowe, Steven M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763257/
https://ncbi.nlm.nih.gov/pubmed/31524633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI131652
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