Hypocretin-2-Saporin Lesions of the Lateral Hypothalamus Produce Narcoleptic-Like Sleep Behavior in the Rat

Hypocretins (Hcrts) are recently discovered peptides linked to the human sleep disorder narcolepsy. Humans with narcolepsy have decreased numbers of Hcrt neurons and Hcrt-null mice also have narcoleptic symptoms. Hcrt neurons are located only in the lateral hypothalamus (LH) but neither electrolytic...

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Vydáno v:J Neurosci
Hlavní autoři: Gerashchenko, Dmitry, Kohls, Matthew D., Greco, MaryAnn, Waleh, Nahid S., Salin-Pascual, Rafael, Kilduff, Thomas S., Lappi, Douglas A., Shiromani, Priyattam J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2001
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762996/
https://ncbi.nlm.nih.gov/pubmed/11549737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-18-07273.2001
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