Familial Amyloid Polyneuropathy: Receptor for Advanced Glycation End Products-Dependent Triggering of Neuronal Inflammatory and Apoptotic Pathways

Familial amyloid polyneuropathy (FAP) is a neurodegenerative disorder associated with extracellular deposition of mutant transthyretin (TTR) amyloid fibrils, particularly in the peripheral nervous system. We have hypothesized that binding of TTR fibrils to the receptor for advanced glycation end pro...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Sousa, Mónica Mendes, Du Yan, Shi, Fernandes, Rui, Guimarães, António, Stern, David, Saraiva, Maria João
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2001
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762914/
https://ncbi.nlm.nih.gov/pubmed/11567048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-19-07576.2001
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