Delayed Inner Ear Maturation and Neuronal Loss in PostnatalIgf-1-Deficient Mice

Insulin-like growth factor-1 (IGF-1) has been shown to play a key role during embryonic and postnatal development of the CNS, but its effect on a sensory organ has not been studied in vivo. Therefore, we examined cochlear growth, differentiation, and maturation in Igf-1 gene knock-out mice at postna...

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Publié dans:J Neurosci
Auteurs principaux: Camarero, Guadalupe, Avendaño, Carlos, Fernández-Moreno, Carmen, Villar, Angeles, Contreras, Julio, de Pablo, Flora, Pichel, José G., Varela-Nieto, Isabel
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2001
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ARTICLE
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762913/
https://ncbi.nlm.nih.gov/pubmed/11567053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-19-07630.2001
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