A Comparative Study of Drug Delivery Methods Targeted to the Mouse Inner Ear: Bullostomy Versus Transtympanic Injection

We present two minimally invasive microsurgical techniques in rodents for specific drug delivery into the middle ear so that it may reach the inner ear. The first procedure consists of perforation of the tympanic bulla, termed bullostomy; the second one is a transtympanic injection. Both emulate hum...

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Dades bibliogràfiques
Publicat a:J Vis Exp
Autors principals: Murillo-Cuesta, Silvia, Vallecillo, Néstor, Cediel, Rafael, Celaya, Adelaida M., Lassaletta, Luis, Varela-Nieto, Isabel, Contreras, Julio
Format: Artigo
Idioma:Inglês
Publicat: MyJove Corporation 2017
Matèries:
Medicine
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407703/
https://ncbi.nlm.nih.gov/pubmed/28362376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/54951
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