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A Comparative Study of Drug Delivery Methods Targeted to the Mouse Inner Ear: Bullostomy Versus Transtympanic Injection

We present two minimally invasive microsurgical techniques in rodents for specific drug delivery into the middle ear so that it may reach the inner ear. The first procedure consists of perforation of the tympanic bulla, termed bullostomy; the second one is a transtympanic injection. Both emulate hum...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Murillo-Cuesta, Silvia, Vallecillo, Néstor, Cediel, Rafael, Celaya, Adelaida M., Lassaletta, Luis, Varela-Nieto, Isabel, Contreras, Julio
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407703/
https://ncbi.nlm.nih.gov/pubmed/28362376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/54951
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