Dishevelled Regulates the Metabolism of Amyloid Precursor Protein via Protein Kinase C/Mitogen-Activated Protein Kinase and c-Jun Terminal Kinase

Alzheimer's disease (AD) is a disorder of two pathologies: amyloid plaques, the core of which is a peptide derived from the amyloid precursor protein (APP), and neurofibrillary tangles composed of highly phosphorylated tau. Protein kinase C (PKC) is known to increase non-amyloidogenic α-secreta...

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Publicado no:J Neurosci
Main Authors: Mudher, A., Chapman, S., Richardson, J., Asuni, A., Gibb, G., Pollard, C., Killick, R., Iqbal, T., Raymond, L., Varndell, I., Sheppard, P., Makoff, A., Gower, E., Soden, P. E., Lewis, P., Murphy, M., Golde, T. E., Rupniak, H. T., Anderton, B. H., Lovestone, S.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2001
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ARTICLE
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762860/
https://ncbi.nlm.nih.gov/pubmed/11438574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-14-04987.2001
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