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cAMP-Dependent Protein Kinase Mediates Activity-Regulated Synaptic Targeting of NMDA Receptors

Chronic activity blockade increases synaptic levels of NMDA receptor immunoreactivity in hippocampal neurons. We show here that blockade-induced synaptic NMDA receptors are functional and mediate enhanced excitotoxicity in response to synaptically released glutamate. Activity blockade increased the...

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Bibliografische gegevens
Gepubliceerd in:J Neurosci
Hoofdauteurs: Crump, F. Thomas, Dillman, Keith S., Craig, Ann Marie
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2001
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762832/
https://ncbi.nlm.nih.gov/pubmed/11438583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-14-05079.2001
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