Channel-Lining Residues of the AMPA Receptor M2 Segment: Structural Environment of the Q/R Site and Identification of the Selectivity Filter

In AMPA receptor channels, a single amino acid residue (Q/R site) of the M2 segment controls permeation of calcium ions, single-channel conductance, blockade by intracellular polyamines, and permeation of anions. The structural environment of the Q/R site and its positioning with regard to a narrow...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Kuner, Thomas, Beck, Christine, Sakmann, Bert, Seeburg, Peter H.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2001
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ARTICLE
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762770/
https://ncbi.nlm.nih.gov/pubmed/11404401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-12-04162.2001
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