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Identification of Channel-lining Amino Acid Residues in the Hydrophobic Segment of Colicin Ia
Colicin Ia is a bactericidal protein of 626 amino acid residues that kills its target cell by forming a channel in the inner membrane; it can also form voltage-dependent channels in planar lipid bilayer membranes. The channel-forming activity resides in the carboxy-terminal domain of ∼177 residues....
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Rockefeller University Press
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2585860/ https://ncbi.nlm.nih.gov/pubmed/19029376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200810042 |
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