Antisense Knockdown of the Glial Glutamate Transporter GLT-1, But Not the Neuronal Glutamate Transporter EAAC1, Exacerbates Transient Focal Cerebral Ischemia-Induced Neuronal Damage in Rat Brain

Transient focal cerebral ischemia leads to extensive neuronal damage in cerebral cortex and striatum. Normal functioning of glutamate transporters clears the synaptically released glutamate to prevent excitotoxic neuronal death. This study evaluated the functional role of the glial (GLT-1) and neuro...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Rao, Vemuganti L. Raghavendra, Dogan, Aclan, Todd, Kathryn G., Bowen, Kellie K., Kim, Bum-Tae, Rothstein, Jeffrey D., Dempsey, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2001
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ARTICLE
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762628/
https://ncbi.nlm.nih.gov/pubmed/11245672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-06-01876.2001
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