A Unique Role for Fyn in CNS Myelination

We analyzed the role of Fyn tyrosine kinase in CNS myelination by using fyn(−/−) null mutant mice, which express no Fyn protein. We found a severe myelin deficit in forebrain at all ages from 14 d to 1 year. The deficit was maximal at 1 month of age and was similar regardless of mouse strain backgro...

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Publicado en:J Neurosci
Autores principales: Sperber, Brian R., Boyle-Walsh, Éilis A., Engleka, Mark J., Gadue, Paul, Peterson, Alan C., Stein, Paul L., Scherer, Steven S., McMorris, F. Arthur
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2001
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ARTICLE
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762613/
https://ncbi.nlm.nih.gov/pubmed/11245687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-06-02039.2001
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