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GABA Transaminase Inhibition Induces Spontaneous and Enhances Depolarization-Evoked GABA Efflux via Reversal of the GABA Transporter

The GABA transporter can reverse with depolarization, causing nonvesicular GABA release. However, this is thought to occur only under pathological conditions. Patch-clamp recordings were made from rat hippocampal neurons in primary cell cultures. Inhibition of GABA transaminase with the anticonvulsa...

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Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
Hauptverfasser: Wu, Yuanming, Wang, Wengang, Richerson, George B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2001
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762542/
https://ncbi.nlm.nih.gov/pubmed/11306616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-08-02630.2001
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