Increased Seizure Susceptibility in Mice Lacking Metabotropic Glutamate Receptor 7

To study the role of mGlu7 receptors (mGluR7), we used homologous recombination to generate mice lacking this metabotropic receptor subtype (mGluR7(−/−)). After the serendipitous discovery of a sensory stimulus-evoked epileptic phenotype, we tested two convulsant drugs, pentylenetetrazole (PTZ) and...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Sansig, Gilles, Bushell, Trevor J., Clarke, Vernon R. J., Rozov, Andrei, Burnashev, Nail, Portet, Chantal, Gasparini, Fabrizio, Schmutz, Markus, Klebs, Klaus, Shigemoto, Ryuichi, Flor, Peter J., Kuhn, Rainer, Knoepfel, Thomas, Schroeder, Markus, Hampson, David R., Collett, Valerie J., Zhang, Congxiao, Duvoisin, Robert M., Collingridge, Graham L., van der Putten, Herman
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2001
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ARTICLE
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762269/
https://ncbi.nlm.nih.gov/pubmed/11698585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-22-08734.2001
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