Increased Seizure Susceptibility in Mice Lacking Metabotropic Glutamate Receptor 7

To study the role of mGlu7 receptors (mGluR7), we used homologous recombination to generate mice lacking this metabotropic receptor subtype (mGluR7(−/−)). After the serendipitous discovery of a sensory stimulus-evoked epileptic phenotype, we tested two convulsant drugs, pentylenetetrazole (PTZ) and...

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書誌詳細
出版年:J Neurosci
主要な著者: Sansig, Gilles, Bushell, Trevor J., Clarke, Vernon R. J., Rozov, Andrei, Burnashev, Nail, Portet, Chantal, Gasparini, Fabrizio, Schmutz, Markus, Klebs, Klaus, Shigemoto, Ryuichi, Flor, Peter J., Kuhn, Rainer, Knoepfel, Thomas, Schroeder, Markus, Hampson, David R., Collett, Valerie J., Zhang, Congxiao, Duvoisin, Robert M., Collingridge, Graham L., van der Putten, Herman
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 2001
主題:
ARTICLE
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762269/
https://ncbi.nlm.nih.gov/pubmed/11698585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-22-08734.2001
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