Increased Seizure Susceptibility in Mice Lacking Metabotropic Glutamate Receptor 7

To study the role of mGlu7 receptors (mGluR7), we used homologous recombination to generate mice lacking this metabotropic receptor subtype (mGluR7(−/−)). After the serendipitous discovery of a sensory stimulus-evoked epileptic phenotype, we tested two convulsant drugs, pentylenetetrazole (PTZ) and...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neurosci
Prif Awduron: Sansig, Gilles, Bushell, Trevor J., Clarke, Vernon R. J., Rozov, Andrei, Burnashev, Nail, Portet, Chantal, Gasparini, Fabrizio, Schmutz, Markus, Klebs, Klaus, Shigemoto, Ryuichi, Flor, Peter J., Kuhn, Rainer, Knoepfel, Thomas, Schroeder, Markus, Hampson, David R., Collett, Valerie J., Zhang, Congxiao, Duvoisin, Robert M., Collingridge, Graham L., van der Putten, Herman
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 2001
Pynciau:
ARTICLE
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762269/
https://ncbi.nlm.nih.gov/pubmed/11698585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-22-08734.2001
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