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DEFOR: depth- and frequency-based somatic copy number alteration detector

MOTIVATION: Detection of somatic copy number alterations (SCNAs) using high-throughput sequencing has become popular because of rapid developments in sequencing technology. Existing methods do not perform well in calling SCNAs for the unstable tumor genomes. RESULTS: We developed a new method, DEFOR...

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Bibliographic Details
Published in:Bioinformatics
Main Authors: Zhang, He, Zhan, Xiaowei, Brugarolas, James, Xie, Yang
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6761943/
https://ncbi.nlm.nih.gov/pubmed/30860569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz170
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