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Potentiation of Aminoglycoside Lethality by C(4)-Dicarboxylates Requires RpoN in Antibiotic-Tolerant Pseudomonas aeruginosa

Antibiotic tolerance contributes to the inability of standard antimicrobial therapies to clear the chronic Pseudomonas aeruginosa lung infections that often afflict patients with cystic fibrosis (CF). Metabolic potentiation of bactericidal antibiotics with carbon sources has emerged as a promising s...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Hall, Clayton W., Farkas, Eszter, Zhang, Li, Mah, Thien-Fah
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6761562/
https://ncbi.nlm.nih.gov/pubmed/31383655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01313-19
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