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Targeting the alternative sigma factor RpoN to combat virulence in Pseudomonas aeruginosa

Pseudomonas aeruginosa is a Gram-negative, opportunistic pathogen that infects immunocompromised and cystic fibrosis patients. Treatment is difficult due to antibiotic resistance, and new antimicrobials are needed to treat infections. The alternative sigma factor 54 (σ(54), RpoN), regulates many vir...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Lloyd, Megan G., Lundgren, Benjamin R., Hall, Clayton W., Gagnon, Luke B.-P., Mah, Thien-Fah, Moffat, Jennifer F., Nomura, Christopher T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626770/
https://ncbi.nlm.nih.gov/pubmed/28974743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12667-y
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