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Targeting the alternative sigma factor RpoN to combat virulence in Pseudomonas aeruginosa
Pseudomonas aeruginosa is a Gram-negative, opportunistic pathogen that infects immunocompromised and cystic fibrosis patients. Treatment is difficult due to antibiotic resistance, and new antimicrobials are needed to treat infections. The alternative sigma factor 54 (σ(54), RpoN), regulates many vir...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5626770/ https://ncbi.nlm.nih.gov/pubmed/28974743 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12667-y |
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